Sameer Deshpande graduated from the New York Film Academy in 2012. Relocating back to India in 2014, Sameer moved to Mumbai to assist cinematographer Kartik   Vijay. During this period, Sameer worked on numerous advertisements while simultaneously serving as a cinematographer on several short films for up-and-coming   directors.

 Since 2016, Sameer has been working independently as a cinematographer.

 In 2022, Sameer's first feature film as cinematographer, a Kannada language film titled "SOLD", was released. It is currently streaming on JioCinema.

 Residing in Mumbai, Sameer works as a cinematographer in both Mumbai and Bangalore.